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Nuclear Magnetic Resonance

Nuclear Magnetic Resonance (NMR) is one of the principal technologies in the NCPSS.  NMR is an evolving technology which plays increasingly essential roles in biological and biomedical research. Some of the most powerful applications of modern NMR in protein research include 1) characterizing protein internal dynamics and probing conformational switch, 2) identifying protein-protein and protein-ligand interactions, especially the weak interactions, 3) investigating structure and dynamics of insoluble proteins such as membrane proteins and aggregated proteins, and 4) measuring the physical properties of intrinsically disordered proteins. The NMR section has been designed and constructed to carry out all above aspects of research as well as develop new methods to meet ad hoc challenges. The NMR facility includes Bruker 600 and 900 MHz NMR spectrometers, Agilent 600, 700 and 800 MHz NMR spectrometers, which can support the large range of NMR applications for the researchers coming from the country.    

 

333 Haike Road, Pudong District,
201210, Shanghai, P.R.China
Tel: 021-20778500
Email: ncpss@sibcb-ncpss.org