Tianlong Zhang , Rong Wang , Zhijing Wang, Xiangxiang Wang, Fang Wang, Jianping Ding. Structural Basis for Ragulator Functioning as a Scaffold in Membrane-anchoring of Rag GTPases and mTORC1. Nat Commun. 2017 Nov 9.
Shicheng Zhang,Linlin Wang,Ye Tao,Tuya Bai,Rong Lu,Tianlong Zhang,Jiangye Chen,Jianping Ding. Structural basis for the functional role of the Shu complex in homologous recombination. Nucleic Acids Res. (2017)
Wei Yang, Weiling Pan, Shuokai Chen, Nicola Trendel, Shutan Jiang, Feng Xiao, Manman Xue, Wei Wu, Zeli Peng, Xiaoxi Li, Hongbin Ji, Xiaolong Liu, Hai Jiang, Haopeng Wang, Hongbin Shen, Omer Dushek, Hua Li, Chenqi Xu. Dynamic regulation of CD28 conformation and signaling by charged lipids and ions. Nat Struct Mol Biol. (2017)
Lunyi Li,Xingdong Guo,Xiaoshan Shi,Changting Li,Wei Wu,Chengsong Yan,Haopeng Wang,Hua Li,Chenqi Xu. Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci USA. (2017)
Yunxiang Zang, Mingliang Jin, Huping Wang, Zhicheng Cui, Liangliang Kong, Caixuan Liu, Yao Cong. Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM. Nat Struct Mol Biol. (2016)
1.Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu, Chengsong Yan, Lijuan Wang, Catharine C. Y. Chang, Tayuan Chang, Ti Zhang, Penghui Zhou, Baoliang Song, Wanli Liu, Shaocong Sun, Xiaolong Liu, Boliang Li & Chenqi Xu. Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism. Nature. (2016)
Xiaohua Ye , Chen Fan , Zhiqiang Ku, Teng Zuo, Liangliang Kong, Chao Zhang, Jinping Shi, Qingwei Liu, Tan Chen, Yingyi Zhang, Wen Jiang, Linqi Zhang, Zhong Huang , Yao Cong. PLOS Pathogens (2016).
Yanjing Li, Jianming Han, Yuebin Zhang, Fang Cao, Zhijun Liu, Shuai Li, Jian Wu, Chunyi Hu, Yan Wang, Jin Shuai, Juan Chen, Liaoran Cao, Dangsheng Li, Pan Shi, Changlin Tian, Jian Zhang, Yali Dou, Guohui Li, Yong Chen & Ming Lei. Structural basis for activity regulation of MLL family methyltransferases. Nature (2016)
Bingbing Wan, Ting Tang, Heather Upton, Jin Shuai, Yuanzhe Zhou, Song Li, Juan Chen, Joseph S Brunzelle, Zhixiong Zeng, Kathleen Collins, Jian Wu, Ming Lei. The Tetrahymena telomerase p75–p45–p19 subcomplex is a unique CST complex. Nat Struct Mol Biol. (2015)
Renfu Shang, Fengjuan Zhang, Beiying Xu, Hairui Xi, Xue Zhang, Weihua Wang, Ligang Wu. Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects. Nature Communications. (2015)
Wei Deng, Jian Wu, Feng Wang, Junko Kanoh, Pierre-Marie Dehe, Haruna Inoue, Juan Chen, Ming Lei. Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2. Cell Res. （2015）
Xiangjun Chen, Weiling Pan, Yinqiang Sui, Hua Li, Xiaoshan Shi, Xingdong Guo, Hai Qi, Chenqi Xu & Wanli Liu. Acidic phospholipids govern the enhanced activation of IgG-B cell receptor. Nature Communications (2015)
Longxing Cao, Xiangyi Shi, Haishuang Chang, Qinfen Zhang, Yongning He. pH-dependent recognition of apoptotic and necrotic cells by the human dendritic cell receptor DEC205. Proc Natl Acad Sci USA. (2015)
Shi Jiao, Zhen Zhang, Chuanchuan Li, Min Huang, Zhubing Shi, Yanyan Wang, Xiaomin Song, Heng Liu, Chunyang Li, Min Chen, Wenjia Wang, Yun Zhao, Zhengfan Jiang, Hongyan Wang, Catherine C L Wong, Chen Wang, Zhaocai Zhou. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. Nat Immunol. (2015)
Ye Wang, Jing Gao, Xingdong Guo, Ti Tong, Xiaoshan Shi, Lunyi Li, Miao Qi, Yajie Wang, Mingjun Cai, Junguang Jiang, Chenqi Xu, Hongbin Ji, Hongda Wang. Regulation of EGFR nanocluster formation by ionic protein-lipid interaction. Cell Res. (2014)
Jing Huang, Andrew F Brown, Jian Wu, Jing Xue, Christopher J Bley, Dustin P Rand, Lijie Wu, Rongguang Zhang, Julian J-L Chen, Ming Lei. Structural basis for protein-RNA recognition in telomerase. Nat Struct Mol Biol. (2014）
Lunyi Li, Xiaoshan Shi, Xingdong Guo, Hua Li, Chenqi Xu. Ionic protein lipid interaction at the plasma membrane: what can the charge do? Trends in Biochemical Sciences. (2014)
Felix Wertek and Chenqi Xu. Digital response in T cells: to be or not to be. Cell Research. (2014):1-2
Xiaoshan Shi, Yunchen Bi, Wei Yang, Xingdong Guo, Yan Jiang, Chanjuan Wan, Lunyi Li, Yibing Bai, Jun Guo, Yujuan Wang, Xiangjun Chen, Bo Wu, Hongbin Sun, Wanli Liu, Junfeng Wang, Chenqi Xu. Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids. Nature. (2013) 493,111-115.