代表性论文
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Lunyi Li,Xingdong Guo,Xiaoshan Shi,Changting Li,Wei Wu,Chengsong Yan,Haopeng Wang,Hua Li,Chenqi Xu. Ionic CD3−Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci USA. (2017)

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Yunxiang Zang, Mingliang Jin, Huping Wang, Zhicheng Cui, Liangliang Kong, Caixuan Liu, Yao Cong. Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM. Nat Struct Mol Biol. (2016)

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Hao Du,Ya Zhao,Jinqiu He,Yao Zhang,Hairui Xi,Mofang Liu,Jinbiao Ma& Ligang Wu. YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex. Nature Communications(2016)
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Kirill Oxenoid, Ying Dong, Chan Cao, Tanxing Cui, Yasemin Sancak, Andrew L. Markhard, Zenon Grabarek, Liangliang Kong, Zhijun Liu, Bo Ouyang, Yao Cong, Vamsi K. Mootha & James J. Chou. Architecture of the Mitochondrial Calcium Uniporter. Nature. (2016)

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Linlin Zhao, Shuqing Wang, Lingyu Du, Jyoti Dev,Liujuan Zhou, Zhijun Liu, James J. Chou &Bo OuYang, Structural basis of interaction between the hepatitis C virus p7 channel and its blocker hexamethylene amiloride,Protein Cell, 2016
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1.Wei Yang, Yibing Bai, Ying Xiong, Jin Zhang, Shuokai Chen, Xiaojun Zheng, Xiangbo Meng, Lunyi Li, Jing Wang, Chenguang Xu, Chengsong Yan, Lijuan Wang, Catharine C. Y. Chang, Tayuan Chang, Ti Zhang, Penghui Zhou, Baoliang Song, Wanli Liu, Shaocong Sun, Xiaolong Liu, Boliang Li & Chenqi Xu. Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism. Nature. (2016)

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Xiaohua Ye , Chen Fan , Zhiqiang Ku, Teng Zuo, Liangliang Kong, Chao Zhang, Jinping Shi, Qingwei Liu, Tan Chen, Yingyi Zhang, Wen Jiang, Linqi Zhang, Zhong Huang , Yao CongPLOS Pathogens (2016).

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Yanjing Li, Jianming Han, Yuebin Zhang, Fang Cao, Zhijun Liu, Shuai Li, Jian Wu, Chunyi Hu, Yan Wang, Jin Shuai, Juan Chen, Liaoran Cao, Dangsheng Li, Pan Shi, Changlin Tian, Jian Zhang, Yali Dou, Guohui Li, Yong Chen & Ming Lei. Structural basis for activity regulation of MLL family methyltransferases. Nature (2016)

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Bingbing Wan, Ting Tang, Heather Upton, Jin Shuai, Yuanzhe Zhou, Song Li, Juan Chen, Joseph S Brunzelle, Zhixiong Zeng, Kathleen Collins, Jian Wu, Ming Lei. The Tetrahymena telomerase p75–p45–p19 subcomplex is a unique CST complex. Nat Struct Mol Biol. (2015)

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Qian Hao, Shi Jiao, Zhubing Shi, Chuanchuan Li, Xia Meng, Zhen Zhang, Yanyan Wang, Xiaomin Song, Wenjia Wang, Rongguang Zhang, Yun Zhao, Catherine CL Wong, Zhaocai Zhou. A non‐canonical role of the p97 complex in RIG‐I antiviral signaling. EMBO J. (2015)

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Renfu Shang, Fengjuan Zhang, Beiying Xu, Hairui Xi, Xue Zhang, Weihua Wang, Ligang Wu. Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects. Nature Communications. (2015) 

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Wei Deng, Jian Wu, Feng Wang, Junko Kanoh, Pierre-Marie Dehe, Haruna Inoue, Juan Chen, Ming Lei. Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2. Cell Res. (2015)

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Xiangjun Chen, Weiling Pan, Yinqiang Sui, Hua Li, Xiaoshan Shi, Xingdong Guo, Hai Qi, Chenqi Xu & Wanli Liu. Acidic phospholipids govern the enhanced activation of IgG-B cell receptor. Nature Communications (2015)

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Longxing Cao, Xiangyi Shi, Haishuang Chang, Qinfen Zhang, Yongning He. pH-dependent recognition of apoptotic and necrotic cells by the human dendritic cell receptor DEC205. Proc Natl Acad Sci USA. (2015)

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Shi Jiao, Zhen Zhang, Chuanchuan Li, Min Huang, Zhubing Shi, Yanyan Wang, Xiaomin Song, Heng Liu, Chunyang Li, Min Chen, Wenjia Wang, Yun Zhao, Zhengfan Jiang, Hongyan Wang, Catherine C L Wong, Chen Wang, Zhaocai Zhou. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. Nat Immunol. (2015)

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Ye Wang, Jing Gao, Xingdong Guo, Ti Tong, Xiaoshan Shi, Lunyi Li, Miao Qi, Yajie Wang, Mingjun Cai, Junguang Jiang, Chenqi Xu, Hongbin Ji, Hongda Wang. Regulation of EGFR nanocluster formation by ionic protein-lipid interaction. Cell Res. (2014)

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Jing Huang, Andrew F Brown, Jian Wu, Jing Xue, Christopher J Bley, Dustin P Rand, Lijie Wu, Rongguang Zhang, Julian J-L Chen, Ming Lei. Structural basis for protein-RNA recognition in telomerase. Nat Struct Mol Biol. (2014)

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Lunyi Li, Xiaoshan Shi, Xingdong Guo, Hua Li, Chenqi Xu. Ionic protein lipid interaction at the plasma membrane: what can the charge do?  Trends in Biochemical Sciences. (2014)

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Shi Jiao, Huizhen Wang, Zhubing Shi, Aimei Dong, Wenjing Zhang, Xiaomin Song, Feng He, Yicui Wang, Zhenzhen Zhang, Wenjia Wang, Xin Wang, Tong Guo, Peixue Li, Yun Zhao, Hongbin Ji, Lei Zhang, Zhaocai Zhou. A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer. Cancer Cell. (2014) 25,166-180.
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Felix Wertek and Chenqi Xu. Digital response in T cells: to be or not to be. Cell Research. (2014):1-2

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Bo OuYang, Shiqi Xie, Marcelo J.Berardi, Xinhao Zhao, Jyoti Dev, Wenjing Yu, Bing Sun, James J.Chou. Unusual architecture of the p7 channel from hepatitis C virus. Nature . (2013) 498,521-525.
 
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Xiaoshan Shi, Yunchen Bi, Wei Yang, Xingdong Guo, Yan Jiang, Chanjuan Wan, Lunyi Li, Yibing Bai, Jun Guo, Yujuan Wang, Xiangjun Chen, Bo Wu, Hongbin Sun, Wanli Liu, Junfeng Wang, Chenqi Xu. Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids. Nature. (2013) 493,111-115.

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